LediHep

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LediHep
Ledihep is a prescription drug and should be used under proper medical guidance and advice.The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Ledipasvir/sofosbuvir was developed by the pharmaceutical company Gilead Sciences and first marketed in October 2014.

LediHep Suppliers Dealers Exporters Distributors Traders in Russia, Ukraine, South Korea, Philippines, Delhi India

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Medicine Details:
Medicine Name: Ledihep

LediHep Suppliers Dealers Exporters Distributors Traders Russia, Ukraine, South Korea, Philippines, Delhi India
Active Ingredients: Sofosbuvir 400 mg and Ledipasvir 90 mg

Ledipasvir/sofosbuvir (trade name Harvoni) is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing 90 mg of the viral NS5A inhibitor ledipasvir and 400 mg of sofosbuvir, a nucleotide inhibitor of the viral RNA polymerase..

1 tablet orally once a day

Duration of Therapy :

  • Therapy-naive patients without cirrhosis : 12 weeks
  • Therapy-naive patients with cirrhosis : 12 weeks
  • Therapy-experienced patients without cirrhosis : 12 weeks
  • Therapy-experienced patients with cirrhosis : 24 weeks

Comments :

    • Relapse rates are affected by baseline host and viral factors and differ between durations of therapy for some subgroups.
    • Therapy-experienced patients are those patients who have failed treatment with either peginterferon alfa/ribavirin or peginterferon alfa/ribavirin/HCV protease inhibitor.
      • Mild or moderate renal dysfunction : No adjustment recommended.
      • Severe renal dysfunction (estimated glomerular filtration rate less than 30 mL/min/1.73 m2).
      • Comments : Safety and efficacy have not been established in patients with severe renal dysfunction; dose not established due to higher exposures of the main sofosbuvir metabolite.

Use : For the treatment of chronic hepatitis C genotype 1/4 infection Ledipasvir/sofosbuvir (trade name Harvoni) is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing 90 mg of Hepatitis C.

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