LediHep Suppliers Dealers Exporters Distributors Traders Russia, Ukraine, South Korea, Philippines, Delhi India
Ledipasvir/sofosbuvir was developed by the pharmaceutical company Gilead Sciences and first marketed in October 2014.
LediHep Suppliers Dealers Exporters Distributors Traders in Russia, Ukraine, South Korea, Philippines, Delhi India
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Medicine Name: Ledihep
Active Ingredients: Sofosbuvir 400 mg and Ledipasvir 90 mg
Ledipasvir/sofosbuvir (trade name Harvoni) is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing 90 mg of the viral NS5A inhibitor ledipasvir and 400 mg of sofosbuvir, a nucleotide inhibitor of the viral RNA polymerase..
1 tablet orally once a day
Duration of Therapy :
- Therapy-naive patients without cirrhosis : 12 weeks
- Therapy-naive patients with cirrhosis : 12 weeks
- Therapy-experienced patients without cirrhosis : 12 weeks
- Therapy-experienced patients with cirrhosis : 24 weeks
- Relapse rates are affected by baseline host and viral factors and differ between durations of therapy for some subgroups.
- Therapy-experienced patients are those patients who have failed treatment with either peginterferon alfa/ribavirin or peginterferon alfa/ribavirin/HCV protease inhibitor.
- Mild or moderate renal dysfunction : No adjustment recommended.
- Severe renal dysfunction (estimated glomerular filtration rate less than 30 mL/min/1.73 m2).
- Comments : Safety and efficacy have not been established in patients with severe renal dysfunction; dose not established due to higher exposures of the main sofosbuvir metabolite.
Use : For the treatment of chronic hepatitis C genotype 1/4 infection Ledipasvir/sofosbuvir (trade name Harvoni) is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing 90 mg of Hepatitis C.
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